Wire, Wyre - it all sounds the same to me!
According to a Warrington RL fan that I met in a pub in Bristol after the 0-0 draw at Ashton Gate the Season before last, he told me they were known as "Wire" because there used to be a lot of wire making factories in the Town. He had curly hair, a beard, glasses, was drinking Real Ale and looked a bit of a geek so this kind of trivia is probably meat and drink to him.
Maddog was there as well but I think she was getting the (non Real) ale in.